on FederalRegister.gov NO open flames. The Public Inspection page may also EPA assessed dietary exposures from trinexapac-ethyl in food as follows: i. Since tolerances and exemptions that are established on the basis of a petition under section 408(d) of FFDCA, such as the tolerance in this final rule, do not require the issuance of a proposed rule, the requirements of the Regulatory Flexibility Act (RFA) (5 U.S.C. These markup elements allow the user to see how the document follows the Palisade is a giberellic acid inhibitor and works primarily by reducing plant height. MODDUS contains trinexapac-ethyl for use as a growth regulator in wheat, barley, oats, rye, triticale, durum wheat and ryegrass seed crops. Inquiry Basket () February,13th,2023; Hebei Luantong trade.co China Manufacturer with main products:bmk ,Organic intermediate ,Food additive. ACTIVE INGREDIENT / BIOLOGICS / COMBINATION, https://iaspub.epa.gov/apex/pesticides/f?p=PPLS:8:::::P8_PUID,P8_RINUM:495794,9198-245, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20200519.pdf, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20170920.pdf, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20140827.pdf, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20090508.pdf, https://www3.epa.gov/pesticides/chem_search/ppls/009198-00245-20090316.pdf. For non-threshold risks, the Agency assumes that any amount of exposure will lead to some degree of risk. Compliance with the tolerance levels specified below is to be determined by measuring only the free and conjugated forms of both trinexapac-ethyl, ethyl 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylate and trinexapac, 4-(cyclopropylhydroxymethylene)-3,5-dioxocyclohexanecarboxylic acid, calculated as the stoichiometric equivalent . Seed weight was generally inversely related to yield; trinexapac-ethyl treatments that produced the highest yield also had the lowest seed weight. By inhibiting gibberellin, trinexapac-ethyl treatment reduces plant height thereby reducing the tendency to lean or fall over. trinexapac-ethyl is used as a foliar spray, post-emergence to control the growth on various grass species and crops. Although EPA recognizes that some individuals would oppose any use of pesticides on food, section 408 of the FFDCA authorizes EPA to set tolerances for residues of pesticide chemicals in or on food when it determines that the tolerance meets the safety standard imposed by that statute. Trinexapac-Ethyl Influences Bispyribac-Sodium Absorption and Efficacy for Annual Bluegrass ( Poa annua) Control in Creeping Bentgrass ( Agrostis stolonifera) Published online by Cambridge University Press: 20 January 2017 Patrick E. McCullough and Stephen E. Hart Article Metrics Save PDF Share Cite Rights & Permissions Abstract documents in the last year, by the Employment and Training Administration This regulation establishes tolerances for residues of trinexapac-ethyl in or on multiple commodities which are identified and discussed later in this document. Following chronic exposure, dose-related neuropathology of the brain was seen at 365/357 mg/kg/day in male and female dogs respectively. EPA has evaluated the available toxicity data and considered its validity, completeness, and reliability as well as the relationship of the results of the studies to human risk. documents in the last year, 36 Quick Resources. The reasons for these are explained in Unit IV.D. (We`ll never share your email address with a third-party.). Developmental rabbit study. Therefore, 40 CFR chapter I is amended as follows: 1. Call a poison control center or doctor for treatment advice If in eyes Hold eye open and rinse slowly and gently with water for 15-20 minutes. 3334, 1301 Constitution Ave. NW, Washington, DC 20460-0001. 1. This repetition of headings to form internal navigation links Pesticide Review Status. Chronic risk. In the mouse, there was no evidence of carcinogenicity. Prevent fire caused by electrostatic discharge steam. documents in the last year, 36 If you are worried about bronzing, tank mix a product that contains manganese rather than iron. To summarize our work, we found a trend for one to two inch reductions in plant height when Palisade or Palisade plus Tilt were applied, but this did not consistently translate to increased grain yield. Information not marked confidential pursuant to 40 CFR part 2 may be disclosed publicly by EPA without prior notice. | Home | Index of common names | Pesticideclassification| SiteMap| the Federal Register. In terms of revenue, the global top. I provided 2013 results in a blog post last year, and this post provides an update including our 2014 findings. Chemical Review Manager: Kelly Ballard (ballard.kelly@epa.gov), 703-305-8126. Federal Register issue. include documents scheduled for later issues, at the request Open for Comment, Economic Sanctions & Foreign Assets Control, Electric Vehicle Standards and Requirements, Further Advancing Racial Equity and Support for Underserved Communities Through the Federal Government, Addendum to the Human Health Risk Assessment for Trinexapac-ethyl, Revised Residue Chemistry Chapter for Triexapac-ethyl. 02/28/2023, 828 on NW., Washington, DC 20460-0001; telephone number: (703) 347-8072; email address: benbow.bethany@epa.gov. Product Name: Trinexapac-ethyl: CAS No. Therefore, acute aggregate risk is equivalent to the acute dietary risk as discussed in Unit III.C.1.i. Superintendents across the Southeast are looking for ways to maintain their golf course with fewer staff members. Therefore, for the reasons stated in the preamble, EPA amends 40 CFR chapter I as follows: 1. These effects in the dog study were observed only at high doses (>357 mg/kg/day) and with chronic exposure, and no associated neurological signs or other neuropathology were observed. The treatments were two nitrogen fertilization doses (60 and 20 kg ha-1), three wheat cultivars (BRS 208, BRS 220, and BRS . Acute risk. documents in the last year, 522 1029 0 obj <>/Filter/FlateDecode/ID[<9B9F72845FCBC54B95A1BA019DA6AE45>]/Index[1016 20]/Info 1015 0 R/Length 73/Prev 68852/Root 1017 0 R/Size 1036/Type/XRef/W[1 2 1]>>stream Getting the most out of these applications is more important than ever as every minute of maintenance is especially valuable during these challenging times. 321(q), 346a and 371. corresponding official PDF file on govinfo.gov. A Rule by the Environmental Protection Agency on 11/04/2020. documents in the last year, 861 The method may be requested from: Chief, Analytical Chemistry Branch, Environmental Science Center, 701 Mapes Rd., Ft. Meade, MD 20755-5350; telephone number: (410) 305-2905; email address: residuemethods@epa.gov. All rights reserved. documents in the last year, by the Federal Highway Administration documents in the last year, 83 The goal to is to apply trinexapac-ethyl only to the leaf as this is the only route of uptake into the plant. Based on the residential use patterns for trinexapac-ethyl, chronic residential exposure to residues is not expected. It acts in the best interests of the game for the continued enjoyment of those who love and play it. The name " " is approved in China for trinexapac and for trinexapac-ethyl. A summary of the toxicological endpoints for trinexapac-ethyl used for human risk assessment is shown in Table 1 of this unit. documents in the last year, by the Employment and Training Administration publication in the future. documents in the last year, 822 L. 104-4). This action directly regulates growers, food processors, food handlers, and food retailers, not States or Tribes, nor does this action alter the relationships or distribution of power and responsibilities established by Congress in the preemption provisions of FFDCA section 408(n)(4). All documents in the docket are listed in the docket index available at http://www.regulations.gov. Those assessments rely on tolerance-level residues, 2019 default processing factors, and an assumption of 100% crop treated (PCT). EPA determines whether acute and chronic dietary pesticide exposures are safe by comparing aggregate exposure estimates to the aPAD and cPAD. This regulation is effective November 4, 2020. There are no established or proposed Codex, Canadian, or Mexican MRLs for trinexapac-ethyl in or on any food or feed crops.Start Printed Page 12745. All Rights Reserved. Information not marked confidential pursuant to 40 CFR part 2 may be disclosed publicly by EPA without prior notice. . The objective of this work was to evaluate the effect of trinexapac-ethyl and nitrogen doses on the agronomic performance and grain yield of three wheat cultivars. Do NOT wash away into sewer. Contact us today for pricing & size information. with the Chemical Abstracts Service number 95266-40-3. Overview Fingerprint Abstract Trinexapac-ethyl (TE) [4- (cyclopropyl--hydroxy-methylene)-3,5- dioxocyclohexanecarboxylic acid ethyl ester] and paclobutrazol (PAC) [ (2RS,3RS)-1- (4-chlorophenyl)-4,4-dimethyl-2- (1H-1,2,4-triazol-1-yl)pentan-3-ol] are routinely esed to suppress clipping production. All other brand names used on this website are Trademarks of other manufacturers in which proprietary rights may exist. Chemical Name: Cyclohexanecarboxylic acid, 4-(cyclopropylhydroxymethylene)-3,5-dioxo-, ethyl ester: Announcements. (b) Section 18 emergency exemptions. Palisade is a giberellic acid inhibitor and works primarily by reducing plant height. Wheat plant heightas affected by plant growth regulators in 2013, Wheat plant height as affected by plant growth regulator in 2014. Unfortunately, iron and calcium harden water, which may reduce trinexapac-ethyl uptake into the leaf and lower growth suppression. EPA will submit a report containing this rule and other required information to the U.S. Senate, the U.S. House of Representatives, and the Comptroller General of the United States prior to publication of this final rule in the Federal Register. In the Federal Register of March 3, 2020 (85 FR 12454) (FRL-10005-58), EPA issued a document pursuant to FFDCA section 408(d)(3), 21 U.S.C. More information and documentation can be found in our The President of the United States issues other types of documents, including but not limited to; memoranda, notices, determinations, letters, messages, and orders. establishing the XML-based Federal Register as an ACFR-sanctioned documents in the last year, 287 I the absence of weakened stems due to freeze or disease, most lodging in wheat is caused by failure of the root anchorage system (root lodging). Further information about EPA's risk assessment and determination of safety can be found at http://www.regulations.gov in the document titled Trinexapac-ethyl. Use spark-proof tools and explosion-proof equipment. For complete information about, and access to, our official publications 95266-40-3 - RVKCCVTVZORVGD-QXMHVHEDSA-N - Trinexapac-ethyl [ISO] - Similar structures search, synonyms, formulas, resource links, and other chemical information. This site displays a prototype of a Web 2.0 version of the daily Syngenta Crop Protection, Inc. requested these tolerances under the Federal Food, Drug, and Cosmetic Act (FFDCA). Remove all sources of ignition. Residential handler exposure scenarios for both dermal and inhalation are considered to be short-term only, due to the infrequent use patterns associated with homeowner products. EPA may establish a tolerance that is different from a Codex MRL; however, FFDCA section 408(b)(4) requires that EPA explain the reasons for departing from the Codex level. Formula: C 16 H 24 O 5 Si; Molecular weight: 324.4443; . The following list of North American Industrial Classification System (NAICS) codes is not intended to be exhaustive, but rather provides a guide to help readers determine whether this document applies to them. The United States is not able to harmonize its sugarcane tolerance with the Codex MRL; based on the reduction of the preharvest interval (PHI) from 28 to 14 days on sugarcane, the field trial data indicate that use in accordance with the label results in residues may exceed tolerances if they were harmonized with Codex. For information regarding EPA's efforts to determine which chemicals have a common mechanism of toxicity and to evaluate the cumulative effects of such chemicals, see EPA's Web site at http://www.epa.gov/pesticides/cumulative. Other names: Trinexapac-ethyl, trimethylsilyl ether Permanent link for this species. This regulation is effective March 2, 2012. Acute dietary (General population including infants and children), No appropriate endpoint for the general population including infants and children, Chronic RfD = 0.32 mg/kg/day cPAD = 0.32 mg/kg/day. Discharge into the environment must be avoided. Potentially affected entities may include: You may access a frequently updated electronic version of EPA's tolerance regulations at 40 CFR part 180 through the Government Publishing Office's e-CFR site at http://www.ecfr.gov/cgi-bin/text-idx?&c=ecfr&tpl=/ecfrbrowse/Title40/40tab_02.tpl. Conversely, when larger carrier volumes are used, the coarser spray droplets result in reduced foliar coverage. Use dry chemical, carbon dioxide or alcohol-resistant foam. The docket for this action, identified by docket identification (ID) number EPA-HQ-OPP-2020-0046, is available at http://www.regulations.gov or at the Office of Pesticide Programs Regulatory Public Docket (OPP Docket) in the Environmental Protection Agency Docket Center (EPA/DC), West William Jefferson Clinton Bldg., Rm. Chromatog Trinexepac-ethyl Brand: PrimeraOne Downloads: Label , SDS Containing the same active ingreedient as PRIMO MAXX; PrimeraONE Trinexapac-Ethyl will make your course greener and reduce the number of mowings, saving labor, fuel, and time. What are the uses of Trinexapac-ethyl ? and services, go to Slowing flushes of warm-season turf growth with applications of trinexapac-ethyl i.e., Primo MAXX or post-patent products is an important part of reducing mowing inputs and other labor costs. Trinexapac-ethyl EPA registers pesticides under Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). documents in the last year, 940 Trade Capacity. menu. Relevant information about this document from Regulations.gov provides additional context. on NARA's archives.gov. New Documents Manganese and trinexapac-ethyl are compatible and seem to yield higher turf growth suppression than trinexapac-ethyl and iron. EPA's assessment of exposures and risks associated with trinexapac-ethyl follows. These markup elements allow the user to see how the document follows the Incidental oral (short and intermediate-term), No appropriate endpoint for the incidental oral scenario for children, Dermal & Inhalation (short- and intermediate-term-adults only), Dermal (or oral) study NOAEL = 60 mg/kg/day (dermal absorption rate = 77.5%. Section 408(b)(2)(A)(i) of FFDCA allows EPA to establish a tolerance (the legal limit for a pesticide chemical residue in or on a food) only if EPA determines that the tolerance is safe. Section 408(b)(2)(A)(ii) of FFDCA defines safe to mean that there is a reasonable certainty that no harm will result from aggregate exposure to the pesticide chemical residue, including all anticipated dietary exposures and all other exposures for which there is reliable information. This includes exposure through drinking water and in residential settings, but does not include occupational exposure. 321(q), 346a and 371. ii. This prototype edition of the Uncertainty/safety factors (U/SF) are used in conjunction with the POD to calculate a safe exposure levelgenerally referred to as a population-adjusted dose (PAD) or a reference dose (RfD)and a safe margin of exposure (MOE). There are clear NOAELs/LOAELs for this effect; in which the NOAEL dose is 10-fold lower than the LOAEL dose at which neuropathology is observed, and is therefore sufficiently protective. In addition, this action does not impose any enforceable duty or contain any unfunded mandate as described under Title II of the Unfunded Mandates Reform Act (UMRA) (2 U.S.C. Buy high purity Trinexapac-ethyl analytical standards from Chem Service Inc. Shop N-13706-250MG today for special offers and discounted shipping. This action does not contain any information collections subject to OMB approval under the Paperwork Reduction Act (PRA) (44 U.S.C. This MRL is different than the tolerances established for trinexapac-ethyl in the United States. The telephone number for the Public Reading Room is (202) 566-1744, and the telephone number for the OPP Docket is (703) 305-5805. Please note that, to comply with Canada's . Table 2.2.3, Tolerance Summary for Trinexapac-ethyl summarizes these differences on page 8 of the document, Trinexapac-ethyl: Human Health Risk Assessment for the Section 3 Registration Action on Cereal Grains, Sugarcane, and Grasses Grown for Seed which is located in docket ID number EPA-HQ-OPP-2010-0524. document.write(" Hide\u00A0index<\/span><\/a>\u00A0|") the material on FederalRegister.gov is accurately displayed, consistent with While application of Palisade resulted in numeric reductions in plant height at Chickasha and Stillwater, differences among treatments were not statistically significant. Classification: Not likely to be Carcinogenic to Humans. DEEMTM 7.81 default concentration factors were used to estimate residues of trinexapac-ethyl in processed commodities. Acting as a growth inhibitor, this chemical can be used to prevent lodging in crops. This final rule establishes tolerances under section 408(d) of FFDCA in response to petitions submitted to the Agency. Dietary Exposure Evaluation Model (DEEMTM) 7.81 default concentration factors were used to estimate residues of trinexapac-ethyl in processed commodities. The USGA promotes and conserves the true spirit of the game of golf as embodied in its ancient and honorable traditions. Section 408(b)(2)(D)(v) of FFDCA requires that, when considering whether to establish, modify, or revoke a tolerance, the Agency consider available information concerning the cumulative effects of a particular pesticide's residues and other substances that have a common mechanism of toxicity. EPA has not found trinexapac-ethyl to share a common mechanism of toxicity with any other substances, and trinexapac-ethyl does not appear to produce a toxic metabolite produced by other substances. Key words: Leaf architecture, yield components, plant growth, plant growth regulator, Zea mays L. 4. This table of contents is a navigational tool, processed from the Employees. documents in the last year, by the Federal Communications Commission [FR Doc. Based on these risk assessments, EPA concludes that there is a reasonable certainty that no harm will result to the general population, or to infants and children from aggregate exposure to trinexapac-ethyl residues. informational resource until the Administrative Committee of the Federal This information is not part of the official Federal Register document. are not part of the published document itself. * * *. Recommendations may change as further research is conducted and new information is obtained.