Most of these side effects do not require medical attention and will resolve gradually over time. Their mode of action is to disrupt normal bone remodeling, which . amazonamazon I was in a bad way. I had settled on a very low dose of Seroxat, enough to keep withdrawal at bay but not enough to have a therapeutic effect, because I didnt need one. Alendronic acid (bisphosphonate) is a prescription medication used to help your bones stay as strong as possible. Hi By this time my body was still, so I went home feeling scared and utterly distraught. I had open heart surgery at the end of December and didnt take the alendronate for a couple of weeks and coincidentally the swelling went I thought maybe it was caused by fluid build up due to my heart condition and thats why it was better. Its been a nightmare for four weeks weeks. Cyclophosphamide (NSC-26271, Cytoxan) Monohydrate is a nitrogen mustard alkylating agent, it attaches the alkyl group to the guanine base of DNA, shown to crosslink DNA, causing strand breakage and . I will make sure I get it. 4. I will not be taking another one! She used to get upset stomach the day & day after taking them. It was becoming clear to me at this point that activity brought on my symptoms, and at that time it was extreme activity a session at the gym, a long bike ride, a strenuous walk. If you suddenly stop taking the drug, you might experience severe side effects, putting you at high risk of more bone fractures. I just started my first pill of fosamax 70 yesterday. He said the result was impossible and after another Dexa scan Im told I have osteopenia in my hip and spine. However Im convinced that its the AA tablet and am very scared to take another! The whole remit of Western medicine is to treat symptoms without curing, so that long term profits can be made. I better print your reviews kind people & put them before my GP & the Liver Consultant who suggested bisphosphonates in the first place!! The efficacy of this approach is enhanced by aminobisphosphonates such as zoledronic acid and alendronic acid, both of which promote the accumulation of stimulatory phosphoantigens in target cells. It will slow down the breakdown of bones and support the faster growth of new bones in your body. Do not take alendronate if you have low calcium levels. So I have decided that it must be the alendronic acid and I have stopped taking them its making my life unbearable. Please tell your doctor if youre taking: Your doctor might recommend you take brands of alendronic acid such as Fosavance and Bentexo along with vitamin D3 (calciferol). I feel much better and fitter than before. Hi there. I have also been taking Adcal tablets for years. Ive only taken one tablet going to speak to Dr tomorrow. Researching I came across Dr Rex Newnham, his story is very interesting, look him up he has written several books re osteoporosis/arthritis, treating them naturally with borax/boron. I Have been taking Alendronic Acid Tablets for 11 months now. Hi, my story is very similar but I only found out today that Alendronic Acid has caused my dental problems. She had dizzy spells, blackouts, feeling sick etc and doctors said she had Temperol Arteritis. Sister told the doc she intends taking Boron. However, the pressure was on. Alendronic Acid has a side effect of causing hair loss and tiredness. prunus . In fact we were three quarters of the way through our time together before I happened to mention I took alendronic acid. All Rights Reserved. Not far into the walk (about 20 mins. I would demand one straight away. I walked home very gingerly with the dog and later phoned my doctor Peripheral neuropathy in the hands and fingers. who told me it could be one of many things. I have had to keep off coffee, fruit and anything acidic for months, I even tried gaviscon which made me feel sick and had a bloated stomach for 2 hours. My advice beware. From 2013 I was prescribed alendronic acid. So I left the surgery with a prescription for alendronic acid and a promise I would have a scan after two years, not the usual three. This helps to improve bone strength and makes the bone less fragile. Taking Prednisone now reduced to 15mg per day and apparently it has accelerated progress of cataracts! Also does anyone know what element of AA gives you the aches and pains so that I know if it will be safer for me to take the Risedronate please? I reported the effect the drug had on me to the MHRA. Instead of the exercising I need and want to be doing, my muscles are weakening, my joints ache, my tendons burn and my bones are probably crumbling away. It has given me bad acid reflux. Think Im off to GP to hear her thoughts!!! Even before Fosamax was introduced in 1995 as a superior osteoporosis treatment, jaw osteonecrosis has been linked to the bisphosphonate drug family. And of course I couldnt exercise, so taking the drug seemed suddenly very important. Withdrawal was so extreme that the longest I ever lasted off the drug was seven weeks, the worst of my life. Took 1 pill of AA. Im just another person looking for help with my bones, having been told by my doctor that there is no alternative to Alendronic Acid. She is very upset as to how this medication has impacted her. I dont think there is enough information from doctors/nurses to explain about Osteoporosis to patients. Who else out there has a similar story? Store the tablet, oral solution, or oral effervescent form of alendronic acid as directed in its packaging. I am 52 but had secondary cancer 18 months after my breast cancer. This was before I started checking and researching EVERY drug I was told I needed. The side effects are horrific. There has to be a better way. Ive just discovered that lack of it can be at the root of fatigue, depression, low body temperature, and many other issues. I had been suffering with a terrible burning tongue for eight months and I also had aching legs, this burning tongue I put down to the gallstones I have got. I had vivid dreams, some headaches and didnt sleep well to start with. I am otherwise healthy and have never taken any meds in my life. The wierd thing is that none of my upper teeth seem to have been affected by it. Im 62. I read its the same Acid in cleaning products! However, you are advised to talk to your doctor if these side effects persist or worsen. I was wondering if the side effects of the drug actually go away, and if they do, how soon can I expect to see some sort of improvement? Terms|Privacy, Research Forum for Enduring Sexual Dysfunction, https://info.mhra.gov.uk/drug-analysis-profiles/dap.html?drug=./UK_EXTERNAL/NONCOMBINED/UK_NON_000837661002.zip&agency=MHRA, https://www.druglawsuitsource.com/canada-fosamax-lawsuits-settled/. Severe side effects include the following: In rare cases, alendronic acid may cause a severe allergic reaction (anaphylaxis). Where do you live Jane hope you dont mind me asking. I am interested about the post that said you should only really take for 2 years does anyone else have info on this. Another problem that really concerns me is that my teeth feel rough, as though the surface is eroding. Many thanks for all your information. It has further become clear that my symptoms were not and are not brought on by activity per se, but by an increase and deepening in my breathing, as if the extra air I take in is poisoning me in some way. I have been reluctant to start this course of medication due to the possible side effects and negative responses from the enquiries I have made regarding the drug. Do not lie down for at least 30 minutes after taking medicine. Do not just stop taking alendronic acid without your doctors approval. We would be very interested in accounts of what happens when people take RxISK reports to doctors. Very useful thread this thanks everyone. GP is arranging for a bone scan . It could give you terrible side effects. If you were prescribed to take 10 mg of alendronic acid, swallow one whole tablet daily. I am worried about it as it seems to be getting worse. cant belive my GP gave me these awful tablets . Hi, Ive just discovered this site. In case of severe allergic reactions and poisoning on your first dose, please call your doctor or emergency help immediately. Like just for a moment I couldnt remember where I kept my masking tape. There are over 200 million people worldwide who have osteoporosis. To summarise, my probs appear to be muscular. It can worsen the side effects of alendronic acid in your stomach and prevent the drug from working. But, theres not enough evidence on this claim. Please talk to your doctor about this. This is just too weird. Reading all above, i think i will put myself on a little break, just to see if there is a difference in my condition overall. I have been told to take kale with spinach and brocoli which is full of calcio blended with almond milk before breakfast and before going to bed. I am 73, have Secondary Progressive Multiple Sclerosis and I was prescribed Aldronic Acid 1 a week since breaking my femur in 2015. My appointment is on the 23rd August 1017 and I am now very concerned. I had heard of necrosis in the bones before and she had all the symptoms. If you missed a dose, take it the following morning and continue taking your next doses on your usual schedule. Home; About; Program; FAQ; Registration; Sponsorship; Contact; Home; About; Program; FAQ; Registration; Sponsorship . Although a diagnosis of osteoporosis is based on the results of your bone density scan, the decision about what treatment you need, if any, is based on a number of other factors including your: age. Im 62, and fit until I came tumbling of my bicycle 2years ago and damaged my lumbar spine and muscles. Some years later she was in terrible pain and her doctor wouldnt believe me when i said that i thought her hips were dying. I have recently been prescribed AA and, after researching this drug for its possible side effects and reading your stories, I really do not want to take it! My doctor didn't mention the gastrointestinal issues when prescribing Alendronic acid and neither did she mention alternative ways of improving my situation. No way am I taking another drug, and particularly not this one. I also have severe oseaoarthritis in my hip and other joints are affected. Can you give me the name of this book, I too am struggling with whether to go down the road of alendronic acid. I shall be bringing these reviews to my GPs attention AND a refusal to even take the first dose! I will not take the poison again. I do have quite a high reading of osteoporosos but I feel I need to know what it really does to the body. My lower face is completely swollen on the left side. Surgeon said her bones in the hip and pelvis crumbled away like chalk and hed never seen that as severe before. The pain has travelled to her shins since stopping it. My story begins in May 2014 when I was 72 and took the first once a week dose of one tablet with a glass of water. I was told that it was very uncommon what happened to me, and it was my choice to take it again next week or not. If recommended to be taken twice a day, you should have it during lunchtime and dinnertime. Alendronic acid (108) is an aminobiphosphonate used to counter postmenopausal osteoporosis, and acts by inhibiting the activity of osteoclasts, bone cells that are involved in the resorption of bone. ALN has a half-life of about 10 years in humans. Consult your doctor if you experience such side effects. Hi i have been given AA but couldnt take it due to stomach problems now they are thinking of sending me for infusion could i ask what natural solutions u are using as i was told I couldnt replace bone without AA am very worried about an infusion. I drank 2 cups of coffee. A woman from Pembrokeshire says she "has been left with this fear" after a medicine she was taking has weakened her bones. She doesnt have osteoporosis. I read the leaflet and decided to google. The my neck was hurting. She was put on Alendronic acid as she had a fall broke her wrist and has had breast cancer. HELP! At which point he told me that NICE guidelines indicated that he had to prescribe alendronic acid, and he could only move me to a different drug if it didnt work. Then, you can resume eating and drinking normally. But, remember that without medications, you have to supply your body with enough nutrients and exercise to support and strengthen bone growth. Stopping and seeing if the symptoms resolve for most drugs is the best way to prove a link some problems with some drugs may take time more time than you expect but will resolve but some may also be permanent. I also broke my hip, which made it even more difficult to do anything at all. Ive just read your post on this thread about Alendronic Acid & was hoping you might share your naturopathic bone protocol supplementation with me. sex. Now on Alendronic 70 weekly. Nothing too spectacular to report. My whole body is sore. Pharmaceutical form. The PA was baffled. As a consequence, my Dr prescribed Alendronic Acid 70mg. Clinical particulars. Theres little research if alendronic acid is safe for breastfeeding moms. I would say) I was suddenly aware of my mouth being transformed into a state where I was unable to move my lips and then my jaw at all. Ive just been prescribed AA but having read all the posts on this site have decided not to start taking it. Until this doctor expressed his surprise that I was taking it, and his opinion that it was possibly the cause of my problems, no one had ever raised any questions about it. I have even had to report my concern and disappointment and lack of care by both my GP and Dentist. If I took slow shallow breaths the pain was bearable. These drugs are pushed to the top of the prescribing line by big pharma. Hello very interested in everyones comments, I was put on alendronic acid tablets two years ago since I had osteoporosis in the hips. Was taken into hospital and because I was taken alendronic they discharged me with 4 Tramadol pain was excruciating..Then I started knocking on doors ring any doctor who would listen no one listen. Due to cutbacks now prescribed unnamed Alendronic and feel absolutely ghastly. Bizarre feelings in my head my heart was pounding and had moments when it seemed out of rhythm. Needless to say I will never take another one and I would like to know whether anyone knows how long Alendronic Acid takes to leave the system. I thought I was intelligent and assertive enough that it couldnt possibly happen to me a second time. I was put on alendronic acid weekly and vitamin d and calcium twice a day . Selleck's Alendronic Acid has been cited by 1 Publication. Just had to reply to your post! Blood test in November showed a underactive thyriod and am taking Levothyronine 25mg. Thank you. Alendronic acid may put your pregnancy at risk. This way, youll prevent any irritation in your throat or esophagus. Started alendronic acid Jul 2014 for three years. Delighted to report Tum is behaving much better since giving up just hoping the other side effects ( Jaw and Teeth) dont show up unexpected! While there is no cure for osteoporosis, your doctor will give you a treatment plan like taking medications and lifestyle changes. Home; About. Have been taking alendronic for 14 months now because I had a fall just over 15months ago and broke both knee caps, have been taking them once a week,but I find they make me dizzy so was thinking of stooping them,is this advisable? 33% of reviewers reported a positive experience, while 47% reported a negative experience. My sister was recently told by her doctor that as she's been on it for over 5 years she should stop taking them for 3 years. judy. My ears was hurting. I chose the infusions and, after two infusions, the Pagets was seen to be in remission. Im not going to take another one and just hope these pains gradually wear off. I have had 7 weeks off work with a fractured wrist and another week off with feeling poorly due to AA (with no pay as Im a self employed carer) and need to feel fully fit before returning to work. They began to itch the next day, ( I took my 5th dose of medication) and they were slightly better but I called my doctor and got in To the office Friday. Your dosing may depend on your age, how severe your bone condition is, other medical conditions you have, and your reaction to the first dose. If prostate cancer spreads to the bones, the cancer can damage them and cause pain. MY blood pressure became high and I was sent for a ECG on the 29th of November which showed I have at somepoint had a mild heart attack which I was unawear of and have now in December been put on Ramipril 2.7mg and Simvastatin 40mg. So I still have not gotten ANY doctor to tell me that the osteo drugs were what CAUSED this but I dont see any other possible cause. Osteoporosis can be prevented. Since taking it I have a painful jaw,dry mouth and severe constipation, bloated stomach and a general,feeling of being unwell I spoke to my GP a few weeks ago about my painful jaw and he told me this was quite common and to carry on taking it but. Glad Im not alone with these problems,thought i was going mad, hi I had zolondronic infusion no problem ,tablets i cant tolerate so I have hit and missed with them ,I told my consultant and the nurses at the hospital but went unanswered said they would sort it ,five weeks a go I fractured my spine so now Im waiting to see what they going to do Ive been honest with them said i skipped a lot cos I felt sick all the time ,Ive opted for infusion,told them that I did tell them ,but now because Ive fractured my spine Im worried that my bone is bad ,bone density scan and hopefully they will sort infusion out for me .I dont like the tablets,I take vitamin d and c .Im trying to help myself just hope its not too late .wouldnt mind I fell off a ladder about two years ago straight onto my back legs and head fell backwards flat and not a broken bone and I had had a density scan just before the fall. I am not hoi going to take anymore Alendronic acid tablets. It belongs to a class of drugs called bisphosphonates. Fast forward to 2019 stared getting pains from my knees traveled throughout my body into my head thought im going to die. No problems with my calcium + vitamin D levels when I started taking medication. If it is common for headaches, dizzy spells and blackout reportsshouldnt this concern those that live alone, for both GP and patient? I hope you are ok. In 2002 I discovered via the internet that I wasnt desperately ill with an anxiety disorder that only Seroxat could fix. Like to leave a reply to louise bird As I was searching through my kitchen drawers, it came to me. I was such an idiot for believing in this drug! She has stopped the tablets. Im very concerned, like you & so many others, about the side effects of AA which I have just started today! I was given alendronic acid tablets, one a week after had fall off my bike swerving to miss a coke can someone dropped and fractured my pelvis. Related Compound Libraries. Suddenly not taking or stopping this medication may cause severe side effects. Im not really happy with the idea of another pill so asked what would happen if I didnt take them and she said I dont know ! You would think that and the fact that in Canada a class action suit was brought against the manufacturers of this drug, would be enough to warrant serious alarm bells. After reading all the reports of strange muscle and joint pain caused by this medication, Im guessing that is the culprit. Had another car ride, but then it flared up again, sometimes I limped all morning. The oral bisphosphonates alendronic acid and risedronate sodium are considered as first-line options for most patients with postmenopausal osteoporosis due to their broad spectrum of anti-fracture efficacy. Alendronic Acid/Colecalciferol Mylan is a medicine that contains two active substances: alendronic acid and colecalciferol.It was to be available as tablets. Yes and i stopped taking them my stomach was so bad i could only chest breathe. When and how you take alendronic acid can affect whether it will work or not. I asked how we would know if it wasnt working, and his reply was that it would be having an effect on my bones after six months and the next scan results would indicate an increased bone density, or not. I felt pressurised to take it saying that I would suffer as I get older if I didnt take it but I am now wondering if it really does any good. In April 2010 I went back to my gym routine, and within a few weeks the second jerking episode occurred.